Advanced paternal age and parental history of schizophrenia
نویسندگان
چکیده
منابع مشابه
Telomere length, family history, and paternal age in schizophrenia
Leukocyte telomere length (LTL) is longer in association with advanced paternal age, but this association has not been examined along with family history (FH) in schizophrenia. LTL was measured by PCR and compared across cases and controls as part of a study to examine the characteristics of paternal age related schizophrenia. The 53 schizophrenia cases had similar mean LTL as 20 controls, alth...
متن کاملOpposite differential risks for autism and schizophrenia based on maternal age, paternal age, and parental age differences
BACKGROUND AND OBJECTIVES Effects of maternal and paternal age on offspring autism and schizophrenia risks have been studied for over three decades, but inconsistent risks have often been found, precluding well-informed speculation on why these age-related risks might exist. METHODOLOGY To help clarify this situation we analysed a massive single population sample from Denmark including the fu...
متن کاملAdvanced paternal age and reproductive outcome.
Women have been increasingly delaying the start of motherhood in recent decades. The same trend is seen also for men. The influence of maternal age on fertility, chromosomal anomalies, pregnancy complications, and impaired perinatal and post-natal outcome of offspring, has been thoroughly investigated, and these aspects are clinically applied during fertility and pregestational counseling. Male...
متن کاملIs There an Association between Advanced Paternal Age and Endophenotype Deficit Levels in Schizophrenia?
The children of older fathers have increased risks of developing schizophrenia spectrum disorders, and among those who develop these disorders, those with older fathers present with more severe clinical symptoms. However, the influence of advanced paternal age on other important domains related to schizophrenia, such as quantitative endophenotype deficit levels, remains unknown. This study inve...
متن کاملAdvancing paternal age and the risk of schizophrenia.
BACKGROUND A major source of new mutations in humans is the male germ line, with mutation rates monotonically increasing as father's age at conception advances, possibly because of accumulating replication errors in spermatogonial cell lines. METHOD We investigated whether the risk of schizophrenia was associated with advancing paternal age in a population-based birth cohort of 87 907 individ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Schizophrenia Research
سال: 2011
ISSN: 0920-9964
DOI: 10.1016/j.schres.2011.08.013